Journal of the Medical Association of Thailand Vol 95, No 11:NOVEMBER 2012 0125-2208 95 11 2012 Nov Single Injection Fascia Iliaca Block for Pain Control after Arthroscopic Anterior Cruciate Ligament Reconstruction: A Randomized, Controlled Trial 1418 EN Malinee Wongswadiwat Panatda Pathanon Wimonrat Sriraj Panaratana Ratanasuwan Yimyaem Sudjai Bunthaothuk Original Article To investigate the effectiveness of using fascia iliaca block for post-operative pain relief after AACLR. After approval by the Ethics Committee for Khon Kaen University (HE510817), the patients were randomly allocated into two groups using a computer-generated random number and concealed by sealed opaque envelopes. FIB was delivered via a 16-gauge Tuohy needle at the PACU. The patients received either 0.25% bupivacaine with adrenaline or 0.9% NSS 40 mL. Morphine consumption, time to first rescue analgesia, Numerical Rating Scale (NRS), side effects, and complication within 24 hours were recorded. Forty-seven patients were enrolled. There was a statistically significant difference in the 24 hours morphine consumption between the bupivacaine and NSS groups (22.1 ± 7.2 and 31.8 ± 9.3 mg, respectively; p < 0.001). Time to first rescue analgesia was significantly longer in the bupivacaine group (4.60 ± 2.2 vs. 2.83 ± 1.6 hour, p 0.003). The difference of resting and on movement pain score were also significant (2.1 (95% CI 1.3-2.8), p < 0.001 and 1.8 (95% CI 1.2-2.4), p < 0.001 respectively. Neither serious side effect nor neurological sequel was found. The fascia iliaca block is effective for providing pain control for at least 24 hours after anterior cruciate ligament reconstruction. This technique is quite easy, safe, and inexpensive to use. Fascia iliaca block Anterior cruciate ligament reconstruction Post-operative pain control Morphine consumption