Journal of the Medical Association of Thailand Vol 92, No 12:DECEMBER 2009 0125-2208 92 12 2009 Dec Pediatric Renal Transplantation: A Single-Center Experience in Northeast Thailand 1635 EN Suwannee Wisanuyotin Apichat Jiravuttipong Original Article To clarify the demographic data, outcomes and complications of renal transplantation in childrenat Srinagarind (university) Hospital. The authors reviewed the medical records of children with end-stage renal disease(ESRD) who received renal transplantation at Srinagarind Hospital, Khon Kaen, between August 2001 andJuly 2008. Eight male and seven female patients were identified. Their mean age was 12.8 + 3.2 years (range,5.0-17.6). The major cause of ESRD was a congenital anomaly of the kidneys (53%). All of the childrenreceived cadaveric transplantations and none received induction therapy. Triple immunosuppressive drugscomprising cyclosporine, prednisolone and mycophenolate mofetil were administered to 12 patients. Tacrolimus,instead of cyclosporine, was given to three patients who had received a renal transplant since January 2008.The median follow-up time was 15 months (3 to 82 months). The most frequent complication was urinary tractinfection (40%). Acute graft loss was found in one patient (6.7%) due to graft infarction. Other complicationsincluded herpes viral infection, chronic rejection, acute rejection, severe gingival hyperplasia, myopathy,lymphocele and transitional cell carcinoma of the bladder. Two patients returned to dialysis due to graftinfarction and chronic rejection, respectively. The mean serum creatinine at the last follow-up of the remainingcases was 1.2 + 0.5 mg/dL (range, 0.6-2.3). All of the patients survived. The 1- and 5-year graft survivalrates were 93.3% and 86.7%, respectively. The present study demonstrates the potential for successful outcomes of pediatric renaltransplantation in this resource-limited area. Renal transplantation Children Complication End-stage renal disease