Journal of the Medical Association of Thailand Vol 94, No 2:FEBUARY 2011 (SUPPL.1) 0125-2208 94 2 2011 Feb Fractional Flow Reserve Guided Coronary Revascularization in Drug-Eluting Era in Thai Patients with Borderline Multi-Vessel Coronary Stenoses 25 EN Teeranan Angkananard Nattawut Wongpraparut Damras Tresukosol Pradit Panchavinin Original Article Forty-nine patients with MVD (71 stenotic vessels) underwent FFR-guided revascularization (FFRgroup) compared with forty-nine patients with MVD (79 stenotic vessels) underwent traditional PCI (Traditional group) onthe basis of visual estimation of the stenotic lesion. PCI has been performed in the FFR group patient with FFR value < 0.75,whereas those with FFR value > 0.75 continued on medical treatment. The event rates of chest pain, repeat revascularization,hospitalization, myocardial infarction and death were compared between both groups. Total costs incurred in the catheterizationlaboratory, including the cost of stent, balloon, pressure guide wire, contrast media and other supplies, were computedbetween both groups. In FFR group: in 46 vessels, FFR was 0.87 + 0.06 and PCI was avoided, the other 25 vessels, baseline FFR was 0.65+ 0.09 and were underwent PCI. Two patients proceed CABG. In the traditional PCI group: 79 vessels were underwent PCI.In comparison of event free survival between the FFR and the traditional PCI groups during follow-up (mean follow-up 8.27+ 5.45 vs. 9.49 + 5.39 months), they were not different in MACE, chest pain, repeat revascularization, hospitalization,myocardial infarction and death (8.2% vs. 13.3%, p = 0.33). The average total cost saving per patient was 63,290 Baht (p< 0.001). For patients with borderline MVD, FFR-guided coronary revascularization with drug eluting stent placementcould save a total cost per patient at 63,290 Bath without compromising safety. Fractional flow reserve (FFR) Intermediate Borderline coronary stenosis Drug-eluting Multivessel