Thalassemia, genetic blood disorders, is a global public health problem especially in Southeast Asia and Thailand where both α- and β-thalassemia and hemoglobinopathies are highly prevalent. Today, the scientists focus on many diseases caused by gene defects including thalassemia. There are many methods for prevention and treatment of thalassemia including gene management. Genetic control, stem cell transplantation, and gene modification are examples. To reduce the rate of thalassemia, all people wishing to become pregnant are recommended for genetic testing and counseling, which may reduce the number of children born with the diseases.

Keywords: Thalassemia, Gene

Received 9 Jul 2019 | Revised 13 Sep 2019 | Accepted 18 Sep 2019