J Med Assoc Thai 2009; 92 (11):1470

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Correlation between Myocardial Perfusion Imaging Findings and Cardiac Events
Kositwattanarerk A Mail, Chanika C , Sritara P

Objective: The excellent prognostic value of a normal or near normal stress myocardial perfusion imaging
(MPI) has been confirmed in numerous studies. The aim of the present study was to determine the association
of MPI findings and cardiac events.

Material and Method:
Consecutive patients referred from January 2003 to December 2004 by Nuclear Medicine
Unit in Ramathibodi Hospital for myocardial perfusion imaging were studied. Visual scoring of perfusion
images used 17-segments and a scale of 0-4 was done. Sum stress score (SSS) was generated. Cardiac death,
death from any cause and nonfatal acute myocardial infarction (MI) were considered major cardiac events,
and chest pain and late revascularization > 60 days after testing were considered minor cardiac events.

Results: Of the 320 patients studied, 218 subjects who had complete 1-year follow-up, were enrolled. There
were 99 patients with normal MPI (SSS < 3) and 119 patients with abnormal MPI (SSS > 3). Statistical
significance between cardiac events in two groups (p < 0.001) was detected. Among hard events, there were
three cardiac deaths (of these, 1 occurred in a patient with normal MPI and 2 in those with abnormal MPI)
and no patients had non-fatal MI in both groups. Among minor cardiac events, 17 patients developed chest
pain and 11 patients underwent late revascularization. No patient with normal MPI underwent revascularization
(included early and late revascularization) was found.

These results show that SSS can be used to provide incremental prognostic information beyond
clinical data, which confirms the conclusions drawn from the results of previous studies by using nuclear
stress test results.

Myocardial perfusion imaging, Cardiac events

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