Background: Measles, mumps, and rubella are highly contagious respiratory viruses. Healthcare workers (HCWs) are at high risk for infection and transmission to other HCWs and patients.
Objective: To study the seroprevalence of measles, mumps, and rubella antibodies in HCWs at Thammasat University Hospital, Thailand.
Materials and Methods: This was a descriptive, cross-sectional study in 2017. IgG specific antibodies were measured in serum samples from HCWs: measles and mumps were assessed with an enzyme-linked immunosorbent assay kit, rubella using chemiluminescent microparticle immunoassay.
Results: One hundred and forty HCWs participated: 21 doctors (15%), 73 nurses (52.14%) and 46 other employees (32.86%). The mean age was 29.2+6.36 years: range 20 to 57 years. The prevalence of immunity against measles was 129 (92.14%), rubella 126 (90%) and mumps 82 (58%). Older HCWs had significantly greater seroprevalence for measles (p = 0.002) and mumps (p = 0.033). Previous measles/measles-containing vaccines history had no statistical correlation with immunological status; 10/74 HCWs (13.51%) <29 years of age who had received 2 doses of measles/measles-containing vaccines in line with the EPI (Expanded Program on Immunization) and no later boosters showed no measles immunity.
Conclusion: Mumps antibody seroprevalence was lower than that of measles and rubella. HCWs without immunity to measles and mumps were found in the younger cohort. Despite having previous measles/measles-containing vaccines, HCWs should receive a booster before employment.

Keywords: Antibody, Measles, Rubella, Mumps, Healthcare workers