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Original ArticleOpen Access
HIV-1 Incidence Estimates among Young Thai Men Using IgG-Capture BED-Enzyme Immunoassay (BED-CEIA) during 2005-2006
Kana K 
,
Tabprasit S ,
Chuenchitra T ,
Sirisopana N ,
Rangsin R
,
Tabprasit S ,
Chuenchitra T ,
Sirisopana N ,
Rangsin R Background: Knowledge about the most recent HIV epidemic among young generation in Thailand is crucial
for improving the prevention programs. It is important to distinguish between recent and long-term HIV-1
infections among the sero-surveillance populations to estimate the HIV-1 incidence.
Objective: To obtain the HIV-1 incidence estimates in young Thai men from the HIV-1 sero-surveillance among
the Royal Thai Army (RTA) conscripts inducted between November 2005 and November 2006.
Material and Method: The confirmed HIV-1 positive serum samples obtained from the November 2005, May
2006, and November 2006 rounds of RTA conscripts induction were selected to be included in the study. The
recent HIV-1 infections were detected among the confirmed HIV-1 positive serum samples using an HIV-1 BED
incidence EIA Kit (Calypte HIV-1 BED Incidence EIA, Calypte Biomedical Corporation, Maryland, USA. The
incidence estimates were obtained in each round of the induction using a consensus formula was agreed upon
at the US Centers for Disease Controls and Preventions (CDC).
Results: Eighty seven thousand one hundred seventy eight RTA conscripts were tested for HIV-1 infection
between November 2005 and November 2006. The prevalence of HIV-1 infection was 0.51%, 0.60%, and
0.50% for the period of November 2005, May 2006, and November 2006, respectively. The HIV-1 incidence
estimates were 0.14%/year (95% CI, 0.09-0.20), 0.20% year (95% CI, 0.13-0.28), and 0.17%/year (95% CI,
0.10-0.29) in November 2005, May 2006, and November 2006, respectively.
Conclusion: We reported the HIV-1 incidence estimates obtained from the IgG-capture BED-enzyme immunoassay
(BED-CEIA) method in the RTA conscripts sero-surveillance population. The incidence estimates
were ranging from 0.14% - 0.20%/year between November 2005 and November 2006. The estimates could
serve as the recent baseline information for future HIV prevention interventions in Thailand
Keywords: HIV-1, Immunoenzyme techniques, Immunoglobulin G, Incidence
for improving the prevention programs. It is important to distinguish between recent and long-term HIV-1
infections among the sero-surveillance populations to estimate the HIV-1 incidence.
Objective: To obtain the HIV-1 incidence estimates in young Thai men from the HIV-1 sero-surveillance among
the Royal Thai Army (RTA) conscripts inducted between November 2005 and November 2006.
Material and Method: The confirmed HIV-1 positive serum samples obtained from the November 2005, May
2006, and November 2006 rounds of RTA conscripts induction were selected to be included in the study. The
recent HIV-1 infections were detected among the confirmed HIV-1 positive serum samples using an HIV-1 BED
incidence EIA Kit (Calypte HIV-1 BED Incidence EIA, Calypte Biomedical Corporation, Maryland, USA. The
incidence estimates were obtained in each round of the induction using a consensus formula was agreed upon
at the US Centers for Disease Controls and Preventions (CDC).
Results: Eighty seven thousand one hundred seventy eight RTA conscripts were tested for HIV-1 infection
between November 2005 and November 2006. The prevalence of HIV-1 infection was 0.51%, 0.60%, and
0.50% for the period of November 2005, May 2006, and November 2006, respectively. The HIV-1 incidence
estimates were 0.14%/year (95% CI, 0.09-0.20), 0.20% year (95% CI, 0.13-0.28), and 0.17%/year (95% CI,
0.10-0.29) in November 2005, May 2006, and November 2006, respectively.
Conclusion: We reported the HIV-1 incidence estimates obtained from the IgG-capture BED-enzyme immunoassay
(BED-CEIA) method in the RTA conscripts sero-surveillance population. The incidence estimates
were ranging from 0.14% - 0.20%/year between November 2005 and November 2006. The estimates could
serve as the recent baseline information for future HIV prevention interventions in Thailand
Keywords: HIV-1, Immunoenzyme techniques, Immunoglobulin G, Incidence
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