J Med Assoc Thai 2009; 92 (9):45

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The Impacts of Type 2 Diabetes Mellitus on Bone Markers in the Elderly Thai Women
Pooruk P Mail, Kittimanon N , Janthorn P , Bunyaratavej N

A comparison study of bone turnover between the diabetic type 2 and the non-diabetic patients was
conducted by using the age matching technique. The bone markers of the diabetic type 2 patients showed CTx
= 0.48 ng/ml, NMID osteocalcin = 24.62 ng/ml and PINP = 38.61 ng/ml. All study parameters of bone markers
were higher than the control group. Thus, the diabetic cases with high bone turnover assuredly predisposed
to osteoporosis. The bone change consistently monitored particularly in the diabetic cases could prevent
osteoporosis. The high calcium diets and regular exercises were recommended for the diabetic patients.

Keywords: Bone Markers, Diabetes mellitus type 2, Elderly


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