J Med Assoc Thai 2021; 104 (3):432-7

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The Association between Bone Mineral Density and Complete Blood Count in Postmenopausal Women: A Cross-Sectional Study
Leeyaphan J Mail, Peerakul Y , Sittibusaya C

Objective: To demonstrate the relationship between anemia and complete blood count (CBC) parameters with bone mineral density (BMD) in postmenopausal women.

Materials and Methods: A cross-sectional chart-review study was conducted between November 2017 and June 2019. Three hundred twenty-four postmenopausal women aged 50 years or older who had BMD and CBC results were included in the present study.

Results: The prevalence of osteopenia and osteoporosis diagnosed by T-score were 53.1% and 32.7%, respectively. Simple and multiple linear regression analyses showed that no association between CBC parameter with BMD except basophil count, which was negatively associated with BMD (p=0.011). There was no correlation between anemia and BMD status (p=0.168).

Conclusion: CBC parameters such as hemoglobin or white blood cell count were not statistically correlated with BMD. This is the first study demonstrating that basophil count may be an associated factor for deceased BMD.

Keywords: Postmenopausal women, Bone mineral density, Complete blood count, Basophil

DOI: doi.org/10.35755/jmedassocthai.2021.03.11848

Received 24 August 2020 | Revised 17 November 2020 | Accepted 3 December 2020


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