Quality of life is an important measurement of medical outcome. The objective of the present study was to determine the reliability and validity of the Thai-Modified Function Living Index Cancer questionnaire version 2 (T-FLIC 2) in Non-Small Cell Lung Cancer (NSCLC) patients. The FLIC was developed into Thai version 2 and applied to a sample of 36 in-patients with NSCLC. Reliability was assessed by internal consistency using the Cronbach’s alpha statistic, and validity was checked by construct validity using the factor analysis statistic. Cronbach’s alpha coefficient, equal to 0.8710, showed good reliability. A factor analysis was conducted to examine construct validity. It revealed a 5-factor solution accounting for 58.075 percent of the variance. In conclusion, the T-FLIC 2 is a reliable and valid measurement of the quality of life in NSCLC patients and can be used in clinical trials, studies of outcome and research in oncology.

Keywords: Quality of life, Reliability, Validity, Thai-Modified Function Living Index Cancer questionnaire version 2 (T-FLIC 2)