J Med Assoc Thai 2021; 104 (7):1-4

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The Prevalence of Adenocarcinoma in Non-small Cell Lung Cancer Patients at Chulabhorn Hospital
Supavavej A Mail, Sungkasubun P , Siripaibun J , Chaiwiriyawong W , Chavanisakun C , Sricharunrat T , Triphuridet N , Lamlertthon W

Objective: To study the prevalence of the adenocarcinoma cell type in non-small cell lung cancer cases at Chulabhorn Hospital and examine the correlation between histology type and survival of patients.
Materials and Methods: We examined the medical records of non-small cell lung cancer cases treated in Chulabhorn Hospital from January 2009 to December 2011. Baseline demographic data and cancer treatment information were obtained for survival analyses.
Results: Among 62 cases of non-small cell lung cancer, 67.7% were the adenocarcinoma subtype. The median survival of non-small cell lung cancer cases was 11 months (95% CI; 9.0 to 18.0), 12 months in adenocarcinoma group and 7.4 months in squamous cell carcinoma group. There was statistically significant differences of survival among different histology(p=0.006). There was a slightly higher incidence of adenocarcinoma in the non-smoker group compared with the smoker group, 67.7% vs. 64.7%, respectively. Smoking status was significantly associated with histology subtype (p=0.034).
Conclusion: The adenocarcinoma subtype was found in approximately two-thirds of non-small cell lung cancer cases at Chulabhorn hospital. The median survival of patients with the adenocarcinoma subtype was longer than patients with the squamous cell carcinoma subtype with statistically significant.

Keywords: Adenocarcinoma of lung, Non small cell lung cancer


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