Gastroduodenal intussusception is not a common clinical condition. It is usually caused by transpyloric prolapse of a benign gastric lesion into the duodenum. In the present report, the authors present an extremely rare case of gastroduodenal intussusception in which gastric carcinoma served as the lending point. Pre-operative diagnosis was made from endoscopy and biopsy. The patient was treated successfully by subtotal gastrectomy with D2 lymph node dissection. The clinical presentation, diagnosis, and management of this entity were discussed and the literature was reviewed. Both the condition itself and the leading tumor, gastric carcinoma, are extremely rare and to the authors’ knowledge. This is the first report in Thailand.

Keywords: Gastroduodenal intussusception, Transpyloric prolapse, Gastric cancer