J Med Assoc Thai 2021; 104 (7):1166-71

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Outcomes of Steroid Therapy in Combination with Endoscopic Optic Nerve Decompression Surgery for Direct Traumatic Optic Neuropathy: A Case-Series
Thitiwichienlert S Mail, Noiphithak R

Background: Direct traumatic optic neuropathy (TON) carries a poor prognosis. However, the outcome of this injury is diverse and is related to time to treatment and treatment protocol.

Objective: To evaluate the outcomes of the combined treatment protocol in patients with direct TON.

Materials and Methods: The authors retrospectively reviewed the medical records of patients between January 2015 and August 2019. Main outcome was visual acuity (VA) improvement after the treatment.

Results: Thirteen patients (15 eyes) were included. The mean age was 38.61 years with a range of 13 to 65 years. Initial VA varied from no light perception (NPL) in seven eyes of six patients, light perception (PL) in one eye, counting fingers in two eyes, 20/200 in three eyes, and 20/60 in two eyes. Average timing to treatment was 2.8 days (range 0 to 7 days). There were no side effects of high-dose corticosteroids treatment in all patients. During a follow-up period of three months, six of 13 patients (46.1%) had VA improvement.

Conclusion: Despite poor prognosis of direct TON, the combined treatment protocol provides a favorable successful rate with most patients on having stable vision, and some having visual improvement from reducing intracanalicular pressure of the optic nerve.

Keywords: Endoscopic optic nerve decompression; Traumatic optic neuropathy; Visual acuity; Case series

DOI: doi.org/10.35755/jmedassocthai.2021.07.12657

Received 1 March 2021 | Revised 2 June 2021 | Accepted 4 June 2021

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