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Original ArticleOpen Access
Tramadol Suppository versus Placebo for the Relief of Perineal Pain after Perineorrhaphy: A Randomized Controlled Trial in Thailand
Srimaekarat T 
Objective: This randomized double-blinded control trial was conducted to compare the effectiveness of tramodol and placeborectal suppository for the management of postpartum perineal pain after perineorrhaphy.
Material and Method: One hundred women who gave birth vaginally with episiotomy and a second- or third-degree tear,were randomly assign to receive two tablets of tramadol 50 mg or two tablets of placebo, the pill were physically similar to thereal drug. Pain ratings were recorded immediately after perineorrhaphy, 30 minutes, and 1, 2, 6, 12 and 24 hours after firstdose on a 10-cm visual analogue scale. Side effects and overall opinion were assessed.
Results: Tramadol and placebo had no statistical significances in analgesic properties, assessed by the means of pain ratingat the different time intervals. There were no serious adverse events reported.Conclusion: No differences were found in between Tramadol and placebo in relief perineal pain after perineorrhaphy.
Keywords: Tramadol, Rectal suppository, Perineal pain, Perineorrhaphy
Material and Method: One hundred women who gave birth vaginally with episiotomy and a second- or third-degree tear,were randomly assign to receive two tablets of tramadol 50 mg or two tablets of placebo, the pill were physically similar to thereal drug. Pain ratings were recorded immediately after perineorrhaphy, 30 minutes, and 1, 2, 6, 12 and 24 hours after firstdose on a 10-cm visual analogue scale. Side effects and overall opinion were assessed.
Results: Tramadol and placebo had no statistical significances in analgesic properties, assessed by the means of pain ratingat the different time intervals. There were no serious adverse events reported.Conclusion: No differences were found in between Tramadol and placebo in relief perineal pain after perineorrhaphy.
Keywords: Tramadol, Rectal suppository, Perineal pain, Perineorrhaphy
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