J Med Assoc Thai 2005; 88 (11):19

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Gemcitabine and Radiotherapy in the Treatment of Uterine Cervical Cancer Patients at Phramongkutklao Hospital
Jarruwale P Mail, Tanapat Y , Aimpun P

Objectives: To determine response, complication and survival of uterine cervical cancer patients treated with concurrent gemcitabine radiotherapy.
Material and Method: A retrospective review of medical records of 41 patients with uterine cervical cancer patients, stage IIB and above treated with concurrent gemcitabine radiotherapy from August 2000 to August 2003.
Results: At 6 and 12 months of follow up, the complete response rate was 75.6% and 65.9%. The cumulative probability of survival at 6 and 12 months after treatment was 0.93 and 0.85. The main complications were mild hematologic and nonhematologic toxicities.
Conclusion: Concurrent gemcitabine radiotherapy provided a satisfactory response in patients with uterine cervical cancer with mild toxicity. Long term follow up data is necessary to determine the recurrent rate of this regimen.

Keywords: Cervical cancer, Gemcitabine, Radiotherapy


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