Helicobacter pylori (H.pylori) is known to be the prime factor of peptic ulcer disease as well as NSAID usuage. Although medical treatment of the bacteria can eliminate the problem for more than 90% of the infected people but the cost of treatment is high then acid reducing gastric surgery still has a definite role. The prevalence of H. pylori in peptic ulcer perferation is still unknown also whether vagotomy and gastrectomy could eradicate H. pylori. Now laparoscopic surgery especially the simple repair of the perforation has became routinely used in many part of the world. So acid reducing gastric surgery is a good choice in chronic user of NSAID and also an option for people who have H. pylori infection.

Keywords : Peptic ulcer disease, Helicobacter pylori,Peptic ulcer perforation, Acid reducing gastric surgery