J Med Assoc Thai 2006; 89 (3):157

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The Clinicopathology and Outcome of Post-Infectious Glomerulonephritis: Experience in 36 Adults
Srisawat N Mail, Aroonpoonsub L , Lewsuwan S , Kanjanabuch T , Avihingsanon Y , Praditpornsilpa K , Tungsanga K , Chusil S , Eiam-ong S

Post-infectious glomerulonephritis is one of the most common causes of acute glomerulonephritis. A retrospective study of post-infectious glomerulonephritis at King Chulalongkorn Memorial Hospital, Thailand was performed from January 1999 to December 2005. Among thirty six patients, eight cases were poststreptococcal glomerulonephritis and twenty eight cases were post non-streptococcal Glomerulo Nephritis (GN). Most cases present with edema, hypertension, gross hematuria and nephrotic-range proteinuria. C3 and CH50 commonly were low. Post-streptococcal glomerulonephritis had more aggressive pathology compared to the others. However, the long term outcome was excellent. In the present study the authors found ESRD in only 14.3% (4 out of 28 cases) that reflects the excellent prognosis of post-infectious glomerulonephritis. Of interest, all of the ESRD patients were caused by post non-Streptococcal GN. Even though, no statistic was achieved; it might reflect the aggressiveness of non-Streptococcal pathogen.

Keywords: Post-infectious Glomerulonephritis, Post-streptococcal Glomerulonephritis, Outcome


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