The majority of genital tumors are similar in almost all of the cell types but the frequency is different between children, adolescents, and female adults. The primary site of tumor is similar to the adults, however, the potential of malignant occurrence is higher among children and adolescents. The outline of this article covers clinical manifestation, differential diagnosis, investigation, and management in the particular disease/condition. The challenges of gynecology in children and adolescents are the complexity of physical and mental health, so the approach needs delicate skill and reasoning. Because they are not in full adulthood but in the transitional stage, the multidisciplinary and meticulous approach and management is a substantial issue. Balance and flexibility are the main key of this medical care. Extreme surgical intervention leading to over treatment or ignorance and carelessness leading to under quality of care are challenges facing the doctor.

Keywords: Gynecologic tumor, Childhood, Adolescence