Objective: 1) To study developmental outcomes in patients with global developmental delay (GDD) following rehabilitation. 2) To study associated factors of developmental outcomes in patients with GDD following rehabilitation.

Materials and Methods: The present study was a retrospective descriptive study. GDD patients received rehabilitation program at the Thai Red Cross Rehabilitation Center between January 1, 2014 and December 31, 2019. Data were collected from medical records included demographic data, developmental quotient (DQ) calculated from Denver II, and associated factors determining developmental outcomes.

Results: There were 54 subjects at 29.7 months old in average. When comparing between before and after rehabilitation program, DQ in gross motor and personal-social domain improved significantly (p=0.002 and <0.001). Female gender (adjusted OR 13.66, p=0.005) and no history of chromosomal abnormalities (adjusted OR 3.49, p=0.048) were associated with DQ improvement in gross motor domain. Music therapy (adjusted OR 33.94, p=0.013), term delivery (adjusted OR 28.28, p=0.020), no history of seizure (adjusted OR 16.80, p=0.008), and program duration (adjusted OR 1.08, p=0.032) were associated with personal-social domain.

Conclusion: Following rehabilitation program, patients with GDD improved in gross motor and personal-social domain. Female gender and patients without history of chromosomal abnormalities revealed association with gross motor improvement. In addition, patients without history of seizure, music therapy, term delivery, and program duration were associated with personal-social improvement.

Keywords: Global developmental delay; Pediatric rehabilitation; Denver II; Developmental quotient

DOI: 10.35755/jmedassocthai.2022.10.13683

Received 30 May 2022 | Revised 4 August 2022 | Accepted 17 August 2022