J Med Assoc Thai 2010; 93 (11):242

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Roles of Meditation on Alleviation of Oxidative Stress and Improvement of Antioxidant System
Mahagita C Mail

According to MEDLINE/Pubmed search to December 2009, the modulation effects of meditation on oxidative stresshave been increasingly investigated for acute, short and long term effects. Both invasive and noninvasive measurements havebeen utilized. Long term transcendental and Zen meditators have been showed to diminish oxidative stress seen by areduction of lipid peroxidation and biophoton emission. Glutathione level and activity of antioxidant enzymes (catalase,superoxide dismutase, glutathione peroxidase and glutathione reductase) have been facilitated in Yoga and Sudarshan Kriyapractitioners. One year of Tai Chi training has been reported to promote superoxide dismutase activity and lessen lipidperoxidation. Performing diaphragmatic breathing after exhaustive exercise has attenuated oxidative stress faster thancontrol. These data suggest possible roles of meditation and meditation-based techniques on the decrease of oxidative stresswhich may assist to prevent and/or alleviate deterioration of related diseases. However, further research needs to elucidatethe cellular and molecular mechanisms which remain challenge to accomplish.
Keywords: Meditation, Mind-body intervention, Oxidative stress, Antioxidant, Free radicals

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