J Med Assoc Thai 2010; 93 (12):99

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Hypertension in Thai Children: a Report from a Hospital in Suburban Area
Manopunya S Mail, Khositseth S

Hypertension in children is the major risk for cardiovascular disease in adult. Limited data are available for
hypertension in children in Southeast Asia. To determine the cause, treatment, and long-term outcome of hypertension in Thai
Children, the authors retrospectively studied 62 patients (age <15 years) diagnosed with hypertension at Thammasat
University hospital, from December 01, 2004 through November 30, 2009. The mean age was 9.2 + 4.2 years; median
follow-up 8 months. Fifty five (88.7%) patients had secondary hypertension. Patients presented with stage 2 hypertension
(67.7%), and hypertensive emergency (9.7%). Renal parenchymal disease caused 67.3% of secondary hypertension. End
organ damage included left ventricular hypertrophy (11.3%) and hypertensive retinopathy (6.4%). Hypertensive emergency
was caused mostly by acute poststreptococcal glmoerulnephritis (APSGN, 66.7%). Intravenous diuretic coupled with oral
antihypertensive drugs gave uncontrolled blood pressure in APSGN with hypertensive emergency. Seventy percents of
patients with essential hypertension had obesity. Majority of the patients had controlled hypertension without medication.
Acute poststreptococcal glomerulonephritis remained the common cause of transient hypertension and hypertensive emergency
in Thai children. The high incidence of obesity among essential hypertension in children demonstrated in the present
study should alert Thai pediatrician to measure blood pressure in every obese child. Treatment of childhood hypertension was
associated with good long-term outcome.

Keywords: Hypertension, Children, Obesity, Essential hypertension, Primary hypertension, Left ventricular hypertrophy,
Hypertensive retinopathy, Hypertensive emergency, Acute poststreptococcal glomerulonephritis, Thai.


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