J Med Assoc Thai 2011; 94 (10):87

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The Reality of Osteocalcin as a Marker of Vitamin K2
Bunyaratavej N Mail, Buranasinsup S , Jangsangthong A

The present study showed the correlation between undercarboxylated osteocalcin and vitamin D had a role in
production of the undercarboxylated osteocalcin, when the amount of vitamin D 25 (OH) D, (below 30 ng/ml) was decreased,
the linear correlation (r) between the vitamin D and undercarboxylated osteocalcin were also decreased, r = 0.032 when the
level of vitamin D was risen, the linear correlation was 0.274,unfortunately the study-population had little group of the normal
level of vitamin D due to most of them were vitamin D insufficiency so the authors could not show the more value of ‘r’.
However, the present study confirmed that the role of vitamin D in formation of undercarboxylated osteocalcin (UcOC) which
we recognized the UcOC at the low level of vitamin D will misinterpretation of the level of vitamin K2.

Keywords: Osteocalcin, Vitamin K2, Undercarboxylated-Osteocalcin


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