J Med Assoc Thai 2011; 94 (2):159

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Prevalence of High-Grade Cervical Intraepithelial Neoplasia (CIN) in the Patients with Atypical Squamous Cells of Undetermined Significance (ASC-US) Pap Smears: Hospital Based, Dynamic Population Area
Panyanupap A Mail, Thaweekul Y , Poomtavorn Y , Mairaing K , Suwannarurk K , Pattaraarchachai J , Bhamarapravatana K

Objective: To determine the prevalence of cervical intraepithelial neoplasia (CIN) 2-3 (high-grade CIN) among women withAtypical Squamous Cells of Undetermined Significance (ASC-US) Pap smear.
Material and Method: A retrospective medical record review of 220 women with ASC-US cervical Pap smear, including age,menstruation status, parity, placed of residence, occupation, main complaint, and definite histopathological result betweenJuly 2007 and January 2010 was done.
Results: The prevalence of high-grade CIN 2 and CIN 3 in Thammasat University Hospital were 8.6% and 3.2% respectively.No cancer was found in the present study. There was no statistically significant difference in the prevalence of high-grade CINbetween the patients who were 50 years old or more and those who were younger.
Conclusion: Prevalence of high-grade CIN in women with ASC-US was 11.8%. Immediate colposcopy is recommended inwomen with ASC-US.
Keywords: Pap smear, ASC-US, High grade CIN

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