Invasive, extra-intestinal infection with Vibrio cholerae non-O1, non-O139 is rare especially among children.
Herein the authors report a 12- year-old girl with underlying β-thalassemia status post-splenectomy presenting with V.
cholerae non-O1, non-O139 gastroenteritis with concomitant septicemia. The pathogen was identified from stool and blood
culture and the patient recovered uneventfully after antimicrobial and supportive therapy. A review and comparison of
clinical manifestations and outcomes with the previous four cases of invasive V. cholerae non-O1, non-O139 in postsplenectomy
thalassemic pediatric patients is reported.

Keyword: Vibrio cholera non-O1, non-O139, Gastroenteritis, Septicemia, Thalassemia, Children