J Med Assoc Thai 2011; 94 (3):41

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Clinicopathological Characteristics of Mucinous and Non-Mucinous Adenocarcinoma in the Colon and Rectum in Rajavithi Hospital, Thailand
Jivapaisarnpong P Mail, Boonthongtho K

Background: The clinicopathological characteristics of colorectal mucinous adenocarcinoma (MA) are still controversial.
Most of the reports suggested that MA were associated with worse clinicopathological behavior and poorer prognosis than
non-mucinous adenocarcinoma (NMA) while the others showed no difference.

To compare clinicopathological characteristics and tumor recurrence of MA patients with those in NMA patients.

Material and Method:
During the period of 2000 to 2009 in Rajavithi Hospital, a total of 427 colorectal adenocarcinoma
patient records consisting of 407 NMA and 20 MA were included in this study. Mean age, tumor location, TNM staging at
diagnosis, T- stage, N-stage, preoperative CEA level and recurrent rate of MA patients were compared with those of NMA

The distribution of MA patients for gender, mean age, tumor location, TNM stage and preoperative CEA level were
similar to those of NMA patients (all p > 0.05). Only the tumor recurrence in MA was significantly more common than that
in NMA (p = 0.020, OR = 3.28 (1.14-9.43)), whereas the TNM stage was not significantly different from NMA (p = 0.530).
The metastatic site and pattern of metastasis also showed no statistical significance (p = 0.125).

The prognosis of MA is poorer than NMA. This may be associated with mucinous histological type itself.

Keywords: Colorectal mucinous adenocarcinoma, Mucinous carcinoma of colorectum, Colorectal mucinous carcinoma,
Colorectal carcinoma.

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