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Original ArticleOpen Access
Correlation Between Reid’s Colposcopic Index and Histologic Results from Colposcopically Directed Biopsy in Differentiating High-Grade from Low-Grade Squamous Intraepithelial Lesion at Rajavithi Hospital
Boonlikit S 
Objective: To analyze the correlation and accuracy between Reid’s colposcopic index (RCI) and histologic results from
colposcopically directed biopsy (CDB) in differentiating high-grade squamous intraepithelial lesion (HSIL) from low-grade
squamous intraepithelial lesion (LSIL).
Materials and method: A retrospective analysis of medical records of women who had abnormal Pap smear and underwent
colposcopy, RCI scoring and CDB from January 1st, 2003 to December 31st, 2006 at Rajavithi Hospital was conducted.
Results: One hundred women were included in the present study. Compared with histological diagnosis from CDB, accuracy
for four colposcopic criteria: margin pattern, color, vascular pattern and iodine staining were 73.0%, 79.0%, 75.0% and
69.2%, respectively. Combining these variables into RCI showed 89.0% overall accuracy. Color and vascular pattern
showed a good agreement with histologic results from CDB (Kendall’s tau C = 0.68 and 0.63; p < 0.05). Overall, RCI yielded
a good agreement (Kendall’s tau C = 0.66; p < 0.05).
Conclusion: RCI yields a good correlation with histology from CDB and it has high accuracy in differentiating HSIL from
LSIL.
Keywords: Reid’s colposcopic index, Colposcopically directed biopsy, CDB, RCI, Rajavithi
colposcopically directed biopsy (CDB) in differentiating high-grade squamous intraepithelial lesion (HSIL) from low-grade
squamous intraepithelial lesion (LSIL).
Materials and method: A retrospective analysis of medical records of women who had abnormal Pap smear and underwent
colposcopy, RCI scoring and CDB from January 1st, 2003 to December 31st, 2006 at Rajavithi Hospital was conducted.
Results: One hundred women were included in the present study. Compared with histological diagnosis from CDB, accuracy
for four colposcopic criteria: margin pattern, color, vascular pattern and iodine staining were 73.0%, 79.0%, 75.0% and
69.2%, respectively. Combining these variables into RCI showed 89.0% overall accuracy. Color and vascular pattern
showed a good agreement with histologic results from CDB (Kendall’s tau C = 0.68 and 0.63; p < 0.05). Overall, RCI yielded
a good agreement (Kendall’s tau C = 0.66; p < 0.05).
Conclusion: RCI yields a good correlation with histology from CDB and it has high accuracy in differentiating HSIL from
LSIL.
Keywords: Reid’s colposcopic index, Colposcopically directed biopsy, CDB, RCI, Rajavithi
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