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Original ArticleOpen Access
The Prevalence of Hepatitis B in Premarital Counseling Clinic at Siriraj Hospital
Angsuwathana S 
,
Wongwananuruk T ,
Sirimai K ,
Thamkhantho M ,
Raorungrot C ,
Sukamongkol S
,
Wongwananuruk T ,
Sirimai K ,
Thamkhantho M ,
Raorungrot C ,
Sukamongkol S Objective: To study the prevalence and associating factors of hepatitis B infection in the Premarital Counseling Clinic at
Siriraj Hospital.
Material and Method: The data (medical history, physical examination, and Hepatitis B profile) was collected from medical
records of 740 couples who attended the Premarital Counseling Clinic in Siriraj Hospital between September 2005 and
December 2009 for this retrospective study.
Results: The prevalence of positive HBsAg in couples who attended the Premarital Counseling Clinic, Siriraj Hospital was
4.2%, which was 3.0% in male and 1.2% in female. The mean age of male was 32.9 + 5.1 years old and 30.7 + 3.9 years old
in female. History of hepatitis B vaccination was found less in male (male 6.1% vs. female 8.8%). Four point two percent of
participants were positive HBsAg but negative of HBsAb. Twenty-four couples were at risk or 3.2%. Male gender and history
of no hepatitis B vaccination was significantly associated with positive HBsAg. No significant difference was found between
age and occupation.
Conclusion: The prevalence of positive HBsAg in the Premarital Counseling Clinic, Siriraj Hospital was 4.2%. Male gender
and history of no hepatitis B vaccination had significant association with positive HBsAg.
Keywords: Hepatitis B infection, Premarital counseling, Premarital clinic
Siriraj Hospital.
Material and Method: The data (medical history, physical examination, and Hepatitis B profile) was collected from medical
records of 740 couples who attended the Premarital Counseling Clinic in Siriraj Hospital between September 2005 and
December 2009 for this retrospective study.
Results: The prevalence of positive HBsAg in couples who attended the Premarital Counseling Clinic, Siriraj Hospital was
4.2%, which was 3.0% in male and 1.2% in female. The mean age of male was 32.9 + 5.1 years old and 30.7 + 3.9 years old
in female. History of hepatitis B vaccination was found less in male (male 6.1% vs. female 8.8%). Four point two percent of
participants were positive HBsAg but negative of HBsAb. Twenty-four couples were at risk or 3.2%. Male gender and history
of no hepatitis B vaccination was significantly associated with positive HBsAg. No significant difference was found between
age and occupation.
Conclusion: The prevalence of positive HBsAg in the Premarital Counseling Clinic, Siriraj Hospital was 4.2%. Male gender
and history of no hepatitis B vaccination had significant association with positive HBsAg.
Keywords: Hepatitis B infection, Premarital counseling, Premarital clinic
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