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Original ArticleOpen Access
Impact of Risk Factors for Recurrent Ischemic Stroke in Prasat Neurological Institute
Suanprasert N 
,
Tantirithisak T
,
Tantirithisak T Background: Recurrent strokes are more likely to be more disabling or fatal than first-even strokes. The high frequency ofrecurrences underscores the importance of secondary prevention.
Objective: Investigate risk factors of recurrent ischemic stroke and to compare the outcomes after treatment following theThai stroke guideline between patients with recurrent ischemic stroke and patients without recurrent ischemic stroke.
Material and Method: Sixty-seven patients with recurrent ischemic stroke and 167 patients without recurrent ischemic strokewere included in the present study. All patients were evaluated for demographic data, modifiable risk factors, and treatment.
Results: Patients without recurrent ischemic stroke had better controlled level of systolic blood pressure, diastolic bloodpressure, and higher high-density lipoprotein level than patients with recurrent ischemic stroke. Carotid stenosis was higherin patients with recurrent ischemic stroke (43.3% vs. 28.7%, p = 0.032). Patients with recurrent ischemic stroke receivedstatin therapy (67.2% vs. 86.8%, p = 0.001) and folic acid (61.2% vs. 78.4%, p = 0.007) less than patients without recurrentischemic stroke. The multivariate analysis showed that well controlled diastolic blood pressure (p = 0.014), higher level ofhigh-density lipoprotein (p = 0.010), and receiving of statin (p = 0.002) were associated with decreased incidence of recurrentischemic stroke.
Conclusion: Well-controlled risk factors including blood pressure, fasting blood sugar, high-density lipoprotein, andlow-density lipoprotein were crucial for the protection of recurrent ischemic stroke. Furthermore, the benefits of statin andfolic acid therapies for the protection of recurrent ischemic stroke were emphasized.
Keywords: Recurrent ischemic stroke, Risk factors
Objective: Investigate risk factors of recurrent ischemic stroke and to compare the outcomes after treatment following theThai stroke guideline between patients with recurrent ischemic stroke and patients without recurrent ischemic stroke.
Material and Method: Sixty-seven patients with recurrent ischemic stroke and 167 patients without recurrent ischemic strokewere included in the present study. All patients were evaluated for demographic data, modifiable risk factors, and treatment.
Results: Patients without recurrent ischemic stroke had better controlled level of systolic blood pressure, diastolic bloodpressure, and higher high-density lipoprotein level than patients with recurrent ischemic stroke. Carotid stenosis was higherin patients with recurrent ischemic stroke (43.3% vs. 28.7%, p = 0.032). Patients with recurrent ischemic stroke receivedstatin therapy (67.2% vs. 86.8%, p = 0.001) and folic acid (61.2% vs. 78.4%, p = 0.007) less than patients without recurrentischemic stroke. The multivariate analysis showed that well controlled diastolic blood pressure (p = 0.014), higher level ofhigh-density lipoprotein (p = 0.010), and receiving of statin (p = 0.002) were associated with decreased incidence of recurrentischemic stroke.
Conclusion: Well-controlled risk factors including blood pressure, fasting blood sugar, high-density lipoprotein, andlow-density lipoprotein were crucial for the protection of recurrent ischemic stroke. Furthermore, the benefits of statin andfolic acid therapies for the protection of recurrent ischemic stroke were emphasized.
Keywords: Recurrent ischemic stroke, Risk factors
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