Views: 1,519 | Downloads:
164
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Normal Data of Left Ventricular Parameters in Non-Hypertensive Patients Using 320-Slice Cardiac CT: A Study on Intra- and Interobserver Variability
Jongjirasiri S 
,
Sritara C ,
Waeosak P ,
Laothamatas J
,
Sritara C ,
Waeosak P ,
Laothamatas J Objective: Delineate normal data in a Thai population for global left ventricular function, left ventricular mass (LVM), andLV mass index (LVMI) by gated volumetric CT angiography (CTA).
Material and Method: Two hundred twenty seven patients with intermediate risk factors for CAD were referred for CTcoronary angiography. The non-hypertensive and non-diabetic asymptomatic group was selected with negative coronaryCTA. Pre-condition of mild stenosis or less than 50% area stenosis was consistently met for inclusion in the present study.One hundred fifteen patients were included (31 males, 84 females, age range 38-76 years, mean 54.6 + 7.2 for males and54.0 + 6.8 for females respectively).
Results: Mean EDV, ESV, SV, CO, and EF in male and females were EDV 122.6 + 17.3 vs. 94.9 + 16.6 ml, ESV 48.2 + 9.9 vs.34.1 + 9.1 ml, SV 74.5 + 14.2 vs. 60.8 + 10.6 ml, CO 4.2 + 0.8 vs. 3.6 + 0.7 L and EF 60.6 + 6.6 vs. 64.3 + 5.6% respectively.The mean LVM and LVMI were higher in males than females (LVM 134.6 + 21.4 vs. 96.9 + 20.3 g, and LVMI 76.8 + 12.4vs. 61.1 + 11.56 g/m2). Altman and Bland plot for each of them showed that the mean and standard deviation of the differenceswas constant throughout the range of measurements. Each histogram of differences showed that these differences correspondto approximately normal distribution, indicating that the required assumptions held for the use of 95% limits of agreement arevalid.
Conclusion: Data from this group represents healthy volunteers and this may serve as an important source of informationrepresenting normal reference values to be used for Thai patients.
Keywords: 320-slice cardiac CT, Left ventricular parameters, Normal data
Material and Method: Two hundred twenty seven patients with intermediate risk factors for CAD were referred for CTcoronary angiography. The non-hypertensive and non-diabetic asymptomatic group was selected with negative coronaryCTA. Pre-condition of mild stenosis or less than 50% area stenosis was consistently met for inclusion in the present study.One hundred fifteen patients were included (31 males, 84 females, age range 38-76 years, mean 54.6 + 7.2 for males and54.0 + 6.8 for females respectively).
Results: Mean EDV, ESV, SV, CO, and EF in male and females were EDV 122.6 + 17.3 vs. 94.9 + 16.6 ml, ESV 48.2 + 9.9 vs.34.1 + 9.1 ml, SV 74.5 + 14.2 vs. 60.8 + 10.6 ml, CO 4.2 + 0.8 vs. 3.6 + 0.7 L and EF 60.6 + 6.6 vs. 64.3 + 5.6% respectively.The mean LVM and LVMI were higher in males than females (LVM 134.6 + 21.4 vs. 96.9 + 20.3 g, and LVMI 76.8 + 12.4vs. 61.1 + 11.56 g/m2). Altman and Bland plot for each of them showed that the mean and standard deviation of the differenceswas constant throughout the range of measurements. Each histogram of differences showed that these differences correspondto approximately normal distribution, indicating that the required assumptions held for the use of 95% limits of agreement arevalid.
Conclusion: Data from this group represents healthy volunteers and this may serve as an important source of informationrepresenting normal reference values to be used for Thai patients.
Keywords: 320-slice cardiac CT, Left ventricular parameters, Normal data
Download:
PDF