Objective: The purposes of the present study were (1) to study the meaning of Health-Related Quality of Life (HRQoL) from the insider’s perspective and (2) to explore the relevant psychosocial adjustments involved in the HRQoL of Thai 12-to-17-year-old adolescents with repaired cleft lip and cleft palate (CLP).
Material and Method: The study included a sample of 18 adolescents with non-syndromic repaired CLP and 6 parents of these adolescents. The participants were recruited from an orthodontic clinic in the Faculty of Dentistry, Mahidol University, and all were in-depth interviewed.
Results: HRQoL can be categorized into four domains: physical symptoms, functional limitations, emotional well-being and social well-being. In the affected group they were striking differences in psychological assets, psychosocial resources and socioeconomic disparities. The majority of these participants were well-adjusted and able to cope with the adversities they experienced as a result of their conditions; hence it was noted that, participants with consistent support from parents, friends and professionals were likely to have a positive health status and satisfaction with treatment.
Conclusion: These findings have important implications in measuring a multidimensional HRQoL construct , and will enhance issues regarding adaptation strategies which have an impact on HRQoL of adolescents with CLP.

Keywords: Health-Related Quality of life, Cleft lip, Cleft palate, CLP