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Case ReportOpen Access

A Recalcitrant Acrodermatitis Continua of Hallopeau Successfully Treated with Etanercept

Silpa-archa N , Wongpraparut C

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Silpa-archa N, Wongpraparut C. A Recalcitrant Acrodermatitis Continua of Hallopeau Successfully Treated with Etanercept. J Med Assoc Thai 2011;94:1154.

Acrodermatitis continua of Hallopeau (ACH) is considered as a localized form of pustular psoriasis that is usuallyrefractory to the treatment. The condition is characterized by sterile pustules, onychodystrophy, anonychia, and osteolysis ofdistal phalanges. The authors report a case of recalcitrant ACH who previously failed to topical corticosteroid, methotrexate,acitretin, and phototherapy and rapidly responded to etanercept in combination with acitretin. The primary varicella infectionoccurred during the therapy. The patient was able to discontinue etanercept within four months after starting the treatment.The lesion was then under-controlled by acitretin and topical clobetasol ointment with an 8-month clinical remission.
Keywords: Acrodermatitis continua of Hallopeau, Pustular psoriasis, Etanercept, Varicella infection

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