Material and Method: The data were retrospectively collected for patients undergoing SILC, and CMILC at Hat Yai Hospital between September 2009 and October 2011. The operative time, hospital stay, postoperative pain, number of narcotic doses, conversion to open surgery, and postoperative complication were analyzed.

Results: Of SILC/CMILC groups, 107/108 subjects, the mean operative time was 81.1/74.4 minutes, and SILC was statistically longer (p < 0.001). Among SILC/CMILC group, 9/0 cases required the extra ports, as well as 2/5 cases of conversion to open surgery. The mean length of stay of SILC/CMILC was statistically longer of 4.6/3.7 days (p = 0.04), in contrast with the mean postoperative pain at 8 hours was statistically lower of 3.4/4.2 (p = 0.03). Both groups, the postoperative complication had similar proportion.

Conclusion: Preliminary results of the present study showed SILC to be safe compared with CMILC, although operative times were longer.

Keywords: Single-incision laparoscopic cholecystectomy, Conventional Multiple-incision Laparoscopic Cholecystectomy