Views: 1,550 | Downloads:
186
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Case ReportOpen Access
Granulomatous Mycosis Fungoides with Large Cell Transformation Misdiagnosed as Leprosy
Siriphukpong S 
,
Pattanaprichakul P ,
Sitthinamsuwan P ,
Karoopongse E
,
Pattanaprichakul P ,
Sitthinamsuwan P ,
Karoopongse E Background: Granulomatous mycosis fungoides is an unusual histopathological variant of cutaneous T-cell lymphoma
without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have
rarely been reported in the literature.
Case Report: The authors described a case of granulomatous MF stage IIB with large cell transformation who initially
presented with leprosy-like condition and chronic left peroneal neuropathy. The patient received six courses of gemcitabine
with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam
radiation.
Conclusion: Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and
immunohistochemical finding to support the diagnosis of lymphoma.
Keywords: Granulomatous mycosis fungoides, Large cell transformation, Granuloma annulare-like, Leprosy
without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have
rarely been reported in the literature.
Case Report: The authors described a case of granulomatous MF stage IIB with large cell transformation who initially
presented with leprosy-like condition and chronic left peroneal neuropathy. The patient received six courses of gemcitabine
with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam
radiation.
Conclusion: Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and
immunohistochemical finding to support the diagnosis of lymphoma.
Keywords: Granulomatous mycosis fungoides, Large cell transformation, Granuloma annulare-like, Leprosy
Download:
PDF