Objective: To assess the prevalence of Rh-negative pregnant women who attended the antenatal clinic and delivered in Rajavithi Hospital.
Material and Method: A descriptive retrospective study in Rh-negative pregnant women was done. The present study included the general characteristic of cases, anti-D immunoglobulin prophylaxis administration, fetal anemia and neonatal jaundice.
Results: During the study period, 147 Rh-negative pregnant women delivered at Rajavithi Hospital. The prevalence of Rh-negative pregnant women in Rajavithi hospital was 0.31%. Fetal anemia and neonatal jaundice were detected in 21.9% and 37.2%, respectively, and 68.14% of cases received antenatal anti-D immunoglobulin. Anti-D immunoglobulin prophylaxis significantly reduced the incidence of neonatal jaundice (p < 0.05).
Conclusion: The prevalence of Rh-negative pregnant women was 0.31%.

Keywords: Rh-negative, Anti-D immunoglobulin prophylaxis, Neonatal jaundice