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Original ArticleOpen Access
Central Corneal Thickness in the Central Retinal Vein Occlusion Fellow Eyes
Wanichwecharungruang B 
,
Laophulsuk V ,
Sopitanont S ,
Vanichvaranont S ,
Harncharoen K
,
Laophulsuk V ,
Sopitanont S ,
Vanichvaranont S ,
Harncharoen K Objective: To investigate the central corneal thickness (CCT) in the central retinal vein occlusion fellow eye (CRVO-fellow
eye) patients.
Material and Method: A cross-sectional study with 97 CRVO-fellow eye patients and 112 healthy subjects. Three
measurements of CCT were obtained with ultrasonic pachymetry.
Results: Mean age of CRVO-fellow eye was higher than controls, 59.7 + 10.3 vs. 46.4 + 5.8 years, (p < 0.001). Males were
more prevalent in CRVO-fellow eye than in the controls, 47.4% vs. 25%, (p = 0.001). In CRVO-fellow eye group, systemic
diseases were more prevalent. Glaucoma and ocular hypertension were detected in 23 eyes (23.7%) of CRVO-fellow eye.
Mean CCT of CRVO-fellow eye was thinner than controls, 529.2 + 30.3 vs. 543.3 + 31.8 μm, (p = 0.001). Multiple linear
regression models adjusted for age, sex, diabetes, hypertension, cup-to-disc ratio, IOP, and axial length revealed that mean
CCT of CRVO-fellow eye was 16.9 μm thinner than controls.
Conclusion: CRVO-fellow eye patients have thinner CCT than controls. The pathophysiology of this association is unclear.
It may be related to less lamina cribosa rigidity in the thin corneal eye. Lamina cribosa displacement may compress central
retinal vein, leading to CRVO.
Keywords: Central retinal vein occlusion, Central corneal thickness, Optic nerve head, Lamina cribosa, Ocular biomechanics,
Corneal biomechanics, Glaucoma
eye) patients.
Material and Method: A cross-sectional study with 97 CRVO-fellow eye patients and 112 healthy subjects. Three
measurements of CCT were obtained with ultrasonic pachymetry.
Results: Mean age of CRVO-fellow eye was higher than controls, 59.7 + 10.3 vs. 46.4 + 5.8 years, (p < 0.001). Males were
more prevalent in CRVO-fellow eye than in the controls, 47.4% vs. 25%, (p = 0.001). In CRVO-fellow eye group, systemic
diseases were more prevalent. Glaucoma and ocular hypertension were detected in 23 eyes (23.7%) of CRVO-fellow eye.
Mean CCT of CRVO-fellow eye was thinner than controls, 529.2 + 30.3 vs. 543.3 + 31.8 μm, (p = 0.001). Multiple linear
regression models adjusted for age, sex, diabetes, hypertension, cup-to-disc ratio, IOP, and axial length revealed that mean
CCT of CRVO-fellow eye was 16.9 μm thinner than controls.
Conclusion: CRVO-fellow eye patients have thinner CCT than controls. The pathophysiology of this association is unclear.
It may be related to less lamina cribosa rigidity in the thin corneal eye. Lamina cribosa displacement may compress central
retinal vein, leading to CRVO.
Keywords: Central retinal vein occlusion, Central corneal thickness, Optic nerve head, Lamina cribosa, Ocular biomechanics,
Corneal biomechanics, Glaucoma
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