Objective: To compare efficacy between in-house LED to conventional phototherapy equipment in the treatment of neonatal hyperbilirubinemia at Mae Sot Hospital.

Material and Method: This was a randomized controlled trial. Fifty newborns with hyperbilirubinemia were allocated to LED phototherapy group and conventional group. Baseline characteristics were compared and analyzed by descriptive statistics, exact probability and student t-test, and change in serum bilirubin level was analyzed by multilevel regression analysis.

Results: There were 25 patients in each of the two groups. The median duration of phototherapy in LED group was 25 hours, whereas the conventional group required 48 hours (p<0.001) and the average serum bilirubin level in LED group decreased more rapidly than in conventional group (p = 0.007). Hyperthermia were found in 22 infants from conventional group (88%) compared to 11 infants from LED group (44%) (p = 0.002).

Conclusion: In-house LED phototherapy equipment is more effective than conventional phototherapy in the reduction of serum bilirubin level and occurrence of hyperthermia during treatment is less.

Keywords: Light-emitting diode, Conventional phototherapy, Neonatal hyperbilirubinemia