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Original ArticleOpen Access
The Effectiveness of Clinical Practice Guideline for Nasopharyngeal and Oropharyngeal Cancer to Reduce Acute Treatment Toxicity from Concurrent Chemoradiation
Objective: To evaluate the effectiveness of clinical practice guidline(CPG) for nasopharyngeal carcinoma (NPC) and oropharyngeal carcinoma (OPC) on reducing acute toxicity during concurrent chemoradiation (CRT).
Material and Method: The prospective study enrolled 74 patients diagnosed of NPC and OPC that underwent concurrent CRT.The feasibility of CPG was evaluated.
Results: Each checkpoint in CPG is feasible with 76% compliance of three in four points and 24% complete all points. Overall grade 3 or 4 skin reaction and mucositis are 9 and 8% respectively.
Conclusion: CPG that consisted of preventive methods to reduce acute skin and oral mucosa toxicities in NP and OP patients is easy to follow with 24 to 100% compliance. This can be feasible with consideration about immobilization device and energy treatment machine.
Keywords: Nasopharyngeal cancer, Oropharyngeal cancer, Concurrent chemoradiation
Material and Method: The prospective study enrolled 74 patients diagnosed of NPC and OPC that underwent concurrent CRT.The feasibility of CPG was evaluated.
Results: Each checkpoint in CPG is feasible with 76% compliance of three in four points and 24% complete all points. Overall grade 3 or 4 skin reaction and mucositis are 9 and 8% respectively.
Conclusion: CPG that consisted of preventive methods to reduce acute skin and oral mucosa toxicities in NP and OP patients is easy to follow with 24 to 100% compliance. This can be feasible with consideration about immobilization device and energy treatment machine.
Keywords: Nasopharyngeal cancer, Oropharyngeal cancer, Concurrent chemoradiation
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