Views: 1,400 | Downloads:
18
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Effect of Pravastatin in Treatment of Hypercholesterolemia in Non-insulin- dependent Diabetes Patients
Soonthornpun S 
,
Rattarasarn C ,
Leelawattana R ,
Thamprasit A
,
Rattarasarn C ,
Leelawattana R ,
Thamprasit A To evaluate the efficacy of pravastatin in treatment of hypercholesterolemia in non-insulindependent
diabetes patients, a 6-month trial of once daily 10 mg-pravastatin was studied in 30
patients with fairly, well controlled non-insulin-dependent diabetes mellitus. For 27 patients who
completed the study, serum total cholesterol and low-density lipoprotein cholesterol were significantly
lower 16.7±2.3 and 20.2±3.3% from 286.7±5.9 and 198.6±7.2 mg/dl at before to 232.6±7.9
and 147.8±6.4 mg/dl at 4th week and 237.8±6.4 and 155.0±5.8 mg/dl at 24th week after treatment
with pravastatin, respectively (P0.05). There
was no seriou3 adverse effect except acute hepatitis in one patient who recovered spontaneously after
drug withdrawal. Once daily 10 mg-pravastatin is effective in the treatment of hypercholesterolemia
in patients with non-insulin-dependent diabetes mellitus.
diabetes patients, a 6-month trial of once daily 10 mg-pravastatin was studied in 30
patients with fairly, well controlled non-insulin-dependent diabetes mellitus. For 27 patients who
completed the study, serum total cholesterol and low-density lipoprotein cholesterol were significantly
lower 16.7±2.3 and 20.2±3.3% from 286.7±5.9 and 198.6±7.2 mg/dl at before to 232.6±7.9
and 147.8±6.4 mg/dl at 4th week and 237.8±6.4 and 155.0±5.8 mg/dl at 24th week after treatment
with pravastatin, respectively (P0.05). There
was no seriou3 adverse effect except acute hepatitis in one patient who recovered spontaneously after
drug withdrawal. Once daily 10 mg-pravastatin is effective in the treatment of hypercholesterolemia
in patients with non-insulin-dependent diabetes mellitus.
Download:
PDF