J Med Assoc Thai 1997; 80 (11):715

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Effect of Post-Operative Thyroid Hormone Therapy on the Recurrence of Benign Thyroid Nodules. A Study in Thai Patients
Banchuin C Mail, Panpimarnmas S

The efficacy of postoperative thyroid hormone treatment in prevention of recurrent
thyroid nodule is still controversial. In order to investigate this effect in Thai patients, a retrospective
study was performed on files of 321 post-operative patients with benign thyroid nodules,
who were either on thyroid hormone treatment or not after surgery, and were followed-up for at
least l year. The longest follow-up period was 15 years after surgery. The recurrence of nodules
was determined by palpation. It was found that the recurrent rate in patients with adenoma
who did not receive post-operative thyroid hormone treatment was 20 per cent (16/82 cases)
while there was no recurrence at all (0/25 cases) in the treatment group (p

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