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Original ArticleOpen Access
Azithromycin in the Treatment of Chlamydial Cervicitis and Eradicatiotf !if Ureaplasma Urealyticum in Female Lower Genital Tract
Charoenwatanachokchai A 
,
Chitwarakom A ,
Siriwongrangsun P ,
Pariyasak W ,
Yenyasun N ,
Sukwit S
,
Chitwarakom A ,
Siriwongrangsun P ,
Pariyasak W ,
Yenyasun N ,
Sukwit S From May 1995 to May 1996, thirty-six females with chlamydia! cervicitis were enrolled
at Bangrak Hospital's Venereal Disease Clinic in an open study to assess the efficacy and safety of
a single, 1-gram oral dose of azithromycin. Thirty-five had positive C. trachomatis and one had a
positive Gen-probe test. Twenty-two returned for their first and second follow-ups and 18 came
back for their final follow-up (visit 4). Eradication rate was 100 per cent on all visits. Fourteen patients
were excluded from the final analysis- three had dropped out from the beginning, ten had sexual
intercourse without a condom and one had a positive Gen-probe test but negative C. trachomatis
culture. U. urealyticum was isolated from the vaginal wall of 15 of the 36 cases and eradication rate
was 0 per cent at visit 2 and visit 4. In conclusion, this study shows that a single, 1-gram oral dose of
azithromycin is an effective and well-tolerated alternative therapy for chlamydia! cervicitis.
at Bangrak Hospital's Venereal Disease Clinic in an open study to assess the efficacy and safety of
a single, 1-gram oral dose of azithromycin. Thirty-five had positive C. trachomatis and one had a
positive Gen-probe test. Twenty-two returned for their first and second follow-ups and 18 came
back for their final follow-up (visit 4). Eradication rate was 100 per cent on all visits. Fourteen patients
were excluded from the final analysis- three had dropped out from the beginning, ten had sexual
intercourse without a condom and one had a positive Gen-probe test but negative C. trachomatis
culture. U. urealyticum was isolated from the vaginal wall of 15 of the 36 cases and eradication rate
was 0 per cent at visit 2 and visit 4. In conclusion, this study shows that a single, 1-gram oral dose of
azithromycin is an effective and well-tolerated alternative therapy for chlamydia! cervicitis.
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