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Original ArticleOpen Access
Bone Loss in Oophorectomized Thai Women
This prospective analysis was done in 95 postmenopausal women to observe bone loss
rate between 59 natural and 36 surgical menopausal women with or without hormonal replacement
therapy (HRT). Bone mass measurement was performed at lumbar spines (L1-L4
) and hip by dual
energy X-ray absorptiometer at 0, 6 and 12 months. The results revealed that in the non-HRT
group there was significant faster bone loss rate of lumbar spines (LS) and hip (H) of the surgical
group at 12 months (Natural group : LS = -1.11%, H = +2.38% ; Surgical group : LS = -4.51%, H =
-0.66%, P0.05). This observation showed that without
HRT oophorectomized women had greater magnitude of bone loss than women who entered
menopause naturally.
rate between 59 natural and 36 surgical menopausal women with or without hormonal replacement
therapy (HRT). Bone mass measurement was performed at lumbar spines (L1-L4
) and hip by dual
energy X-ray absorptiometer at 0, 6 and 12 months. The results revealed that in the non-HRT
group there was significant faster bone loss rate of lumbar spines (LS) and hip (H) of the surgical
group at 12 months (Natural group : LS = -1.11%, H = +2.38% ; Surgical group : LS = -4.51%, H =
-0.66%, P0.05). This observation showed that without
HRT oophorectomized women had greater magnitude of bone loss than women who entered
menopause naturally.
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