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Original ArticleOpen Access
Clinicopathological Features Predicting Recurrence of Intracranial Meningiomas
Montriwiwatchai P 
,
Kasantikul V ,
Taecholam C
,
Kasantikul V ,
Taecholam C A series of 11 recurrent meningiomas was studied. Most lesions occurred in women.
The youngest patient was 17 years old and the oldest was 73 years. The mean age was 44 years.
Multifactorial risk factors were involved in the tumor regrowth including age of patients, location
of tumors, adequacy of initial surgery, certain histopathological features and subtypes of tumors.
Tumors in young adults tended to have a rapid interval of regrowth as well as a tendency of
multiple recurrences. Brain invasion, extensive bone and muscle involvement, foci of necrosis and
hemorrhage, high mitotic index, angioblastic and papillary patterns were common pathological
risk factors. Additionally, recurrent tumors may retain their original pathological appearance or
become more aggressive by showing marked cellular pleomorphism. Area of liposarcomatous
component was encountered in one recurrent lesion.
The youngest patient was 17 years old and the oldest was 73 years. The mean age was 44 years.
Multifactorial risk factors were involved in the tumor regrowth including age of patients, location
of tumors, adequacy of initial surgery, certain histopathological features and subtypes of tumors.
Tumors in young adults tended to have a rapid interval of regrowth as well as a tendency of
multiple recurrences. Brain invasion, extensive bone and muscle involvement, foci of necrosis and
hemorrhage, high mitotic index, angioblastic and papillary patterns were common pathological
risk factors. Additionally, recurrent tumors may retain their original pathological appearance or
become more aggressive by showing marked cellular pleomorphism. Area of liposarcomatous
component was encountered in one recurrent lesion.
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