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Original ArticleOpen Access
Total Antioxidant Capacity in Plasma of HIV -Infected Patients
Chanarat N 
,
Chanarat P ,
Suttajit M ,
Chiewsilp D
,
Chanarat P ,
Suttajit M ,
Chiewsilp D Total antioxidant capacity (TAC) of fasting EDTA plasma of 33 healthy and 64 HIVinfected
patients was determined using H202-peroxidase-ABTS technique. The results revealed
that the average TAC in HIV-infected patients was significantly lower than those in healthy
normal persons. (0.161±0.097 vs 0.269±0.081 mmol/L Trolox equivalent, p < 0.05). Total lymphocytes
were also counted using Hycel automatic cell counter and absolute CD4 numbers using
Coulter CD4 manual kit. It was interesting that CD4 count was not correlated with the clinical
symptoms of the patients. This paper suggests that prediction of severity and monitoring of the
disease should be performed by determining both total lymphocyte count and total antioxidant
capacity.
patients was determined using H202-peroxidase-ABTS technique. The results revealed
that the average TAC in HIV-infected patients was significantly lower than those in healthy
normal persons. (0.161±0.097 vs 0.269±0.081 mmol/L Trolox equivalent, p < 0.05). Total lymphocytes
were also counted using Hycel automatic cell counter and absolute CD4 numbers using
Coulter CD4 manual kit. It was interesting that CD4 count was not correlated with the clinical
symptoms of the patients. This paper suggests that prediction of severity and monitoring of the
disease should be performed by determining both total lymphocyte count and total antioxidant
capacity.
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