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Case ReportOpen Access
TRANSFUSION MEDICINE Anti-E as a Cause of Hemolytic Disease of the Newborn
A case of HDN caused by anti-E antibody is reported. A group A, E-positive, hemoglobin E
trait female infant was born from a group A, E-negative, B-thalassemia I hemoglobin E mother.
Hyperbilirubinemia was noted at the first day of life. The DAT was positive. Anti-E was detected
in the maternal serum. Jaundice and anemia occurring to the baby were severe enough to require
phototherapy intervention for 9 days and 50 ml of group A, E-negative packed red blood cells
was transfused. The baby's condition improved. She was discharged at 12 days of age. Follow-up
of the baby at 1 year old showed that she was alive and in good health.
trait female infant was born from a group A, E-negative, B-thalassemia I hemoglobin E mother.
Hyperbilirubinemia was noted at the first day of life. The DAT was positive. Anti-E was detected
in the maternal serum. Jaundice and anemia occurring to the baby were severe enough to require
phototherapy intervention for 9 days and 50 ml of group A, E-negative packed red blood cells
was transfused. The baby's condition improved. She was discharged at 12 days of age. Follow-up
of the baby at 1 year old showed that she was alive and in good health.
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