J Med Assoc Thai 1997; 80 (9):144

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Fever, Skin Rash, Jaundice and Lymphadenopathy after Trichloroethylene Exposure : A Case Report
Chittasobhaktra T Mail, Wannanukul W , Wattanakrai P , Pramoolsinsap C , Sohonslitdsuk A

Trichloroethylene, a chlorinated hydrocarbon has been reported to cause many adverse
health effects. This paper describes a female patient presenting with rather unusual manifestation
secondary to trichloroethylene (TCE) exposure, i.e. hepatitis and generalized dermatitis. The
diagnosis was confirmed by positive skin patch testing with 50 per cent TCE solution. After withdrawal
from the exposure site, her symptoms improved and liver function test returned to baseline
level after a three-months period of follow-up. TCE induced immunologic reaction has been
postulated as the pathological process of this illness.

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