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Original ArticleOpen Access
HLA Class II Allele Frequencies in Northern Thais (Kamphaeng Phet)
Maneemaroj R 
,
Chandanayingyong D ,
Longta K ,
Bejrachandra S
,
Chandanayingyong D ,
Longta K ,
Bejrachandra S The polymorphism of HLA class II genes (HLA-DRBl, -DQA1, -DQBl and -DPBl) was
investigated in 97 normal Northern Thais (NT) from Kamphaeng Phet province using PCR-SSO
typing. Allele frequencies (AF) have been determined. DRB 1 * 1202 ( 17.5% ), DRB 1 * 1502
(16.5%), DQA1*0101 (25.8%), DQA1*0102 (21.7%), DQB1*0502 (22.7%), DPB1*0501 (23.2%)
and DPB1*1301 (22.7%) showed the highest frequencies in each locus. These results were more
similar to those observed in Present-day Thais (PDT) and Central Thais (CT) than Northern Thais
from Chiang Mai (CM) and Dai Lue (DL). However, the data presented in this population study
should be useful in many fields, such as anthropology, organ transplantation, disease susceptibility
and evolutionary genetics.
investigated in 97 normal Northern Thais (NT) from Kamphaeng Phet province using PCR-SSO
typing. Allele frequencies (AF) have been determined. DRB 1 * 1202 ( 17.5% ), DRB 1 * 1502
(16.5%), DQA1*0101 (25.8%), DQA1*0102 (21.7%), DQB1*0502 (22.7%), DPB1*0501 (23.2%)
and DPB1*1301 (22.7%) showed the highest frequencies in each locus. These results were more
similar to those observed in Present-day Thais (PDT) and Central Thais (CT) than Northern Thais
from Chiang Mai (CM) and Dai Lue (DL). However, the data presented in this population study
should be useful in many fields, such as anthropology, organ transplantation, disease susceptibility
and evolutionary genetics.
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