Views: 1,489 | Downloads:
16
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Case ReportOpen Access
Multiple Endocrine Neoplasis Type Ila : A Case Report
Seeherunvong T 
,
Churesigaew S ,
Hemsrichart V
,
Churesigaew S ,
Hemsrichart V The authors reported a twelve year and four-month old girl who had prolonged fever for
2 weeks. Physical examination revealed a painless enlarged thyroid gland with firm consistency.
Hyperparathyroidism was suspected because of hyp·ercalcemia, hypophosphatemia, high level of
serum alkaline phosphatase, and decreased density of long bones. Thyroid scan showed a cold
nodule of the left upper lobe which subsequently proved to be a medullary thyroid carcinoma
by high serum thyrocalcitonin level and pathological examination. Her 24-hour urinary vanillyl
mandelic acid was in the normal range, and abdominal ultrasonography demonstrated normal
adrenal glands. Multiple endocrine neoplasia type Ua (MEN Ila) was diagnosed by medullary
thyroid carcinoma and hyperparathyroidism. However, the fully developed syndrome is characterized
by the combined occurrence of medullary thyroid carcinoma, primary hyperparathyroidism,
and pheochromocytomas. This syndrome is a rare, complex, and potentially lethal
disease so early recognition and family screening are very important.
2 weeks. Physical examination revealed a painless enlarged thyroid gland with firm consistency.
Hyperparathyroidism was suspected because of hyp·ercalcemia, hypophosphatemia, high level of
serum alkaline phosphatase, and decreased density of long bones. Thyroid scan showed a cold
nodule of the left upper lobe which subsequently proved to be a medullary thyroid carcinoma
by high serum thyrocalcitonin level and pathological examination. Her 24-hour urinary vanillyl
mandelic acid was in the normal range, and abdominal ultrasonography demonstrated normal
adrenal glands. Multiple endocrine neoplasia type Ua (MEN Ila) was diagnosed by medullary
thyroid carcinoma and hyperparathyroidism. However, the fully developed syndrome is characterized
by the combined occurrence of medullary thyroid carcinoma, primary hyperparathyroidism,
and pheochromocytomas. This syndrome is a rare, complex, and potentially lethal
disease so early recognition and family screening are very important.
Download:
PDF