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Original ArticleOpen Access
Renal Pathology and Long-term Outcome in Childhood SLE
Sumboonnanonda A 
,
Vongjirad A ,
Suntornpoch V ,
Laohapand T ,
Parichatikanond P
,
Vongjirad A ,
Suntornpoch V ,
Laohapand T ,
Parichatikanond P Renal histology is increasingly used as a guide for therapy and prognosis m SLE but
data in children are few and/or short-term. We assessed renal histological features in 19 children
with SLE to determine whether these features are useful in predicting long-term outcome. Mean
age at biopsy was 10±1.7 years old, male to female ratio was 1:2.8. Fourteen patients (73%) had
diffuse proliferative lupus nephritis. Renal histology was evaluated using an activity index
(AI) and chronicity index (CI). Clinical assessment of renal function at biopsy and outcome
were graded according to urinalysis and serum creatinine. Renal function at biopsy correlated
well with AI (p
data in children are few and/or short-term. We assessed renal histological features in 19 children
with SLE to determine whether these features are useful in predicting long-term outcome. Mean
age at biopsy was 10±1.7 years old, male to female ratio was 1:2.8. Fourteen patients (73%) had
diffuse proliferative lupus nephritis. Renal histology was evaluated using an activity index
(AI) and chronicity index (CI). Clinical assessment of renal function at biopsy and outcome
were graded according to urinalysis and serum creatinine. Renal function at biopsy correlated
well with AI (p
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