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Original ArticleOpen Access
Prolonged Fever due to Mycobacterium Avium Complex (MAC) Disease in Advanced HIV Infection: A Public Health Concern
Suwanagool S 
,
Kolladarungkri T ,
Leelarasamee A ,
Chuenarom V ,
Jearanaisilavong J ,
Chaiprasert A
,
Kolladarungkri T ,
Leelarasamee A ,
Chuenarom V ,
Jearanaisilavong J ,
Chaiprasert A From March 1997 to June 1998, infectious etiologies of prolonged fever was prospectively
investigated in 104 advanced human immunodeficiency virus (HIV) infected patients
admitted to Siriraj Hospital. The etiology could be identified in 91 cases (87.5% ). Of these, blood
cultures from 68 patients yielded mycobacteria and fungi. Mycobacterium avium complex was
the most common blood isolate in 24 per cent of the patients; followed by Mycobacterium tuberculosis
in 20.2 per cent, Cryptococcus neoformans in 5.8 per cent, Penicillium marneffei in 5.8
per cent. During the course of febrile illness, 79 of the 91 patients (86.8%) exhibited focal le'sions.
Weight loss, elevated serum alkaline phosphatase were often found to be significantly more
associated with MAC bacteremia (P
investigated in 104 advanced human immunodeficiency virus (HIV) infected patients
admitted to Siriraj Hospital. The etiology could be identified in 91 cases (87.5% ). Of these, blood
cultures from 68 patients yielded mycobacteria and fungi. Mycobacterium avium complex was
the most common blood isolate in 24 per cent of the patients; followed by Mycobacterium tuberculosis
in 20.2 per cent, Cryptococcus neoformans in 5.8 per cent, Penicillium marneffei in 5.8
per cent. During the course of febrile illness, 79 of the 91 patients (86.8%) exhibited focal le'sions.
Weight loss, elevated serum alkaline phosphatase were often found to be significantly more
associated with MAC bacteremia (P
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