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Original ArticleOpen Access
Effects of Long-term Treatment with Depot Medroxy Progesterone Acetate for Contraception on Estrogenic Activity
Taneepanichskul S 
,
Patrachai S
,
Patrachai S The aims of this study were to evaluate the serum estradiol level and the estrogenic
activity in long-term DMPA users. From 1st January 1996 to 31st December 1996, fifty healthy
women receiving DMPA for contraception for more than 36 months were recruited to the study.
From the study, it was found that the mean duration of DMPA use was 59.1±30.7 months, the
mean serum estradiol was 52.7±15.1 pg/ml and these women did not have problems of estrogen
deficiency. This study revealed that long-term treatment with DMPA should not have any
adverse effects on estrogenic activity.
activity in long-term DMPA users. From 1st January 1996 to 31st December 1996, fifty healthy
women receiving DMPA for contraception for more than 36 months were recruited to the study.
From the study, it was found that the mean duration of DMPA use was 59.1±30.7 months, the
mean serum estradiol was 52.7±15.1 pg/ml and these women did not have problems of estrogen
deficiency. This study revealed that long-term treatment with DMPA should not have any
adverse effects on estrogenic activity.
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